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Table 2 Correlations among Nodal and its related molecules in OCCCas and OEmCas

From: Nodal induces apoptosis and inhibits proliferation in ovarian endometriosis-clear cell carcinoma lesions

 

OCCCa

OEmCa

Nodal

pSmad2

XIAP

bcl2

bax

pGSK-3β

Ki-67

Nodal

pSmad2

XIAP

bcl2

bax

pGSK-3β

Ki-67

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

r (p)

pSmad

0.48

*

*

*

*

*

*

0.25

*

*

*

*

*

*

(0.0003)

      

(0.18)

      

XIAP

0.61

0.46

*

*

*

*

*

0.43

0.1

*

*

*

*

*

(< 0.0001)

(0.0006)

     

(0.02)

(0.57)

     

bcl2

0.14

0.4

0.2

*

*

*

*

0.18

−0.01

−0.29

*

*

*

*

(0.28)

(0.002)

(0.14)

    

(0.3)

(0.93)

(0.13)

    

bax

− 0.06

0.14

− 0.19

0.2

*

*

*

0.4

0.08

0.16

0.26

*

*

*

(0.64)

(0.29)

(0.49)

(0.14)

   

(0.03)

(0.65)

(0.39)

(0.15)

   

pGSK-3β

0.4

0.47

0.4

0.4

0.4

*

*

0.46

0.5

0.61

0.35

0.7

*

*

(0.003)

(0.0005)

(0.003)

(0.002)

(0.003)

  

(0.01)

(0.007)

(0.001)

(0.05)

(0.0001)

  

Ki-67

0.07

0.22

0.11

0.02

0.1

0.46

*

−0.13

0.19

0.36

−0.28

0.36

0.6

*

(0.58)

(0.1)

(0.8)

(0.89)

(0.46)

(0.0006)

 

(0.49)

(0.3)

(0.05)

(0.12)

(0.05)

(0.001)

 

Apoptosis

0.5

0.32

0.25

0.09

0.05

0.24

0.1

0.11

−0.07

−0.19

0.32

0.43

0.32

−0.17

(0.0002)

(0.02)

(0.06)

(0.5)

(0.73)

(0.07)

(0.47)

(0.59)

(0.7)

(0.3)

(0.08)

(0.02)

(0.08)

(0.93)

  1. r, Spearman’s correlation coefficient; *, not examined
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BMC Cancer

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