Fig. 1
From: Changes of N6-methyladenosine modulators promote breast cancer progression
Transcriptional pattern of m6A enzymes in major malignant tumors from ONCOMINE database analysis. a, The heat-map represents data with statistically significant upregulation (red) or downregulation (blue) of m6A factors in various human cancer tissues as compared with their normal control. The numbers in the heatmap indicate the published independent datasets of mRNA microarray experiments. b, Box plots from gene expression data in the The Cancer Genome Atlas (TCGA) database comparing the expression of specific m6A members, including methylases (METTL3, METTL14 and WTAP) and demetylases (FTO and ALKBH5) in normal and BC tissue