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Fig. 4 | BMC Cancer

Fig. 4

From: Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma

Fig. 4

RNA-Seq and validation of selected targets. a Overview of total counts of identified RNA-Seq targets after differential expression analysis between pairs of lymphoma (sub-) entities. b Exemplary heatmaps of differentially expressed targets grouped for (B1) clustering of differentiation molecules, (B2) integrin molecules, and (B3) MYC-related molecules. c Summary of the validation experiment for selected targets via additional MYC/H3K4me3 ChIP enrichment analysis (C1) and additional TAQ-MAN RT-PCR analyses (C2) in BL (Blue-1; BL-2, BL-41), DLBCLneg (Karpas-422; U2932-R1) and DLBCLpos (U2932-R2; Carnaval) cell lines (n = 2 biological replicates)

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