Table 3 Univariate and multivariate regression analysis of skeletal metastasis survival
From: Clinical analysis of patients with skeletal metastasis of lung cancer
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |
Age (<  60 vs. ≥ 60) | 1.619 | 1.183–2.216 | 0.002 | 1.549 | 1.124–2.134 | 0.007 |
Sex (male vs. female) | 1.157 | 0.843–1.587 | 0.338 |  |  |  |
Smoking (nonsmoker vs. smoker) | 1.189 | 0.870–1.623 | 0.141 |  |  |  |
Pathology (NSCLC vs. SCLC) | 1.950 | 1.309–2.904 | 0.000 | 2.045 | 1.373–3.047 | 0.000 |
EGFR (positive vs. negative) | 1.479 | 0.772–2.833 | 0.208 |  |  |  |
Number of distant organ metastasis (only 1 vs. over 2) | 1.058 | 0.722–1.550 | 0.247 |  |  |  |
Chemotherapy (yes vs. no) | 9.155 | 4.584–18.284 | 0.000 | 7.121 | 3.542–14.317 | 0.000 |
Radiation therapy (yes vs. no) | 1.291 | 0.840–1.982 | 0.059 |  |  |  |
Orthopedic surgery (yes vs. no) | 1.691 | 1.142–2.504 | 0.005 | 1.710 | 1.148–2.547 | 0.008 |