From: Clinical analysis of patients with skeletal metastasis of lung cancer
Variable | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Age (<  60 vs. ≥ 60) | 1.538 | 1.159–2.161 | 0.002 | 1.549 | 1.122–2.139 | 0.008 |
Sex (male vs. female) | 1.086 | 0.790–1.492 | 0.595 |  |  |  |
Smoking (nonsmoker vs. smoker) | 1.114 | 0.818–1.517 | 0.473 |  |  |  |
Pathology (NSCLC vs. SCLC) | 1.630 | 1.114–2.385 | 0.008 | 1.711 | 1.157–2.532 | 0.007 |
EGFR (positive vs. negative) | 1.462 | 0.769–2.780 | 0.225 |  |  |  |
Number of distant organ metastasis (only 1 vs. over 2) | 1.177 | 0.812–1.705 | 0.367 |  |  |  |
Chemotherapy (yes vs. no) | 9.827 | 4.939–19.552 | 0.000 | 8.064 | 3.981–16.332 | 0.000 |
Radiation therapy (yes vs. no) | 1.597 | 1.048–2.434 | 0.021 | 1.791 | 1.170–2.742 | 0.007 |
Orthopedic surgery (yes vs. no) | 1.377 | 0.931–2.036 | 0.092 |  |  |  |