Serum and cerebrospinal fluid Neudesin concentration and Neudesin Quotient as potential circulating biomarkers of a primary brain tumor

Table 7 Univariate and multivariate linear regression analysis results for logarithm of serum Neudesin

No	Covariate	β	e^β (95% CI)	P-value
		Univariate linear regression analysis
1	Sex	0.43	1.53 (1.18–1.98)	0.002
2	CSF Neudesin [ng/mL]	0.23	1.26 (1.03–1.54)	0.028
3	Neudesin Quotient	−0.28	0.75 (0.57–0.98)	0.041
4	CSF IL-8 [pg/mL]	−0.0005	0.9995 (0.9991–0.9998)	0.005
5	IL-8 Quotient	−0.0084	0.9917 (0.9856–0.9978)	0.009
6	CSF CCL2 [pg/mL]	−0.0002	0.9998 (0.9996–0.9999)	0.029
7	CCL2 Quotient	−0.04	0.96 (0.93–0.99)	0.012
8	WBC [×10³/μL]	−0.03	0.97 (0.94–0.99)	0.036
9	Na⁺ [mmol/L]	0.05	1.05 (1.02–1.08)	0.005
		Multivariate linear regression analysis
1	CSF Neudesin [ng/mL]	0.62	1.85 (1.64–2.09)	< 0.001
2	Neudesin Quotient	−0.80	0.45 (0.38–0.52)	< 0.001

CI Confidence Interval, CSF cerebrospinal fluid, CCL2 Monocyte Chemotactic Protein 1, IL-8 interleukin 8, Na⁺ sodium, WBC white blood cells count

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