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Table 7 Univariate and multivariate linear regression analysis results for logarithm of serum Neudesin

From: Serum and cerebrospinal fluid Neudesin concentration and Neudesin Quotient as potential circulating biomarkers of a primary brain tumor

No Covariate β eβ (95% CI) P-value
   Univariate linear regression analysis
1 Sex 0.43 1.53 (1.18–1.98) 0.002
2 CSF Neudesin [ng/mL] 0.23 1.26 (1.03–1.54) 0.028
3 Neudesin Quotient −0.28 0.75 (0.57–0.98) 0.041
4 CSF IL-8 [pg/mL] −0.0005 0.9995 (0.9991–0.9998) 0.005
5 IL-8 Quotient −0.0084 0.9917 (0.9856–0.9978) 0.009
6 CSF CCL2 [pg/mL] −0.0002 0.9998 (0.9996–0.9999) 0.029
7 CCL2 Quotient −0.04 0.96 (0.93–0.99) 0.012
8 WBC [×103/μL] −0.03 0.97 (0.94–0.99) 0.036
9 Na+ [mmol/L] 0.05 1.05 (1.02–1.08) 0.005
  Multivariate linear regression analysis
1 CSF Neudesin [ng/mL] 0.62 1.85 (1.64–2.09) < 0.001
2 Neudesin Quotient −0.80 0.45 (0.38–0.52) < 0.001
  1. CI Confidence Interval, CSF cerebrospinal fluid, CCL2 Monocyte Chemotactic Protein 1, IL-8 interleukin 8, Na+ sodium, WBC white blood cells count