Differentiating atypical lipomatous tumors from lipomas with magnetic resonance imaging: a comparison with MDM2 gene amplification status

Table 1 Frequencies, odds ratios and performance parameters for each imaging variable for patients with ALT and lipoma

Variable		ALT	Lipoma	Odds Ratio95% CI)^a	P-value	Sensitivity^b	Specificity^b	PPV^b	NPV^b
Region	Lower limb/trunk	45	48	1.32 (1.12–1.54)	0.002	0.957	0.273	0.682	0.900
	Upper limb	2	18
Tumor size	> 130.0 mm	37	19	2.74 (1.82–4.11)	< 0.001	0.787	0.712	0.661	0.824
	≤ 130.0 mm	10	47
Septation	Thick (> 2 mm)	40	9	6.24 (3.36–11.59)	< 0.001	0.851	0.864	0.816	0.891
	Absent/thin (< 2 mm)	7	57
Contrast enhancement	Presence	42	20	2.95 (2.01–4.31)	< 0.001	0.894	0.697	0.677	0.902
Contrast enhancement	Absence	5	46
Nodules	Presence	9	0	0.81 (0.70–0.92)	0.001	0.191	1.000	1.000	0.635
	Absence	38	66

^aData given as odds ratio (95% confidence interval). ^bSensitivity, specificity, PPV and NPV given for the identification of ALT versus lipoma, respectively. PPV, positive predictive value; NPV, negative predictive value

ISSN: 1471-2407