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Table 1 Frequencies, odds ratios and performance parameters for each imaging variable for patients with ALT and lipoma

From: Differentiating atypical lipomatous tumors from lipomas with magnetic resonance imaging: a comparison with MDM2 gene amplification status

Variable   ALT Lipoma Odds Ratio95% CI)a P-value Sensitivityb Specificityb PPVb NPVb
Region Lower limb/trunk 45 48 1.32 (1.12–1.54) 0.002 0.957 0.273 0.682 0.900
  Upper limb 2 18       
Tumor size > 130.0 mm 37 19 2.74 (1.82–4.11) < 0.001 0.787 0.712 0.661 0.824
  ≤ 130.0 mm 10 47       
Septation Thick (> 2 mm) 40 9 6.24 (3.36–11.59) < 0.001 0.851 0.864 0.816 0.891
  Absent/thin (< 2 mm) 7 57       
Contrast enhancement Presence 42 20 2.95 (2.01–4.31) < 0.001 0.894 0.697 0.677 0.902
Absence 5 46       
Nodules Presence 9 0 0.81 (0.70–0.92) 0.001 0.191 1.000 1.000 0.635
  Absence 38 66       
  1. aData given as odds ratio (95% confidence interval). bSensitivity, specificity, PPV and NPV given for the identification of ALT versus lipoma, respectively. PPV, positive predictive value; NPV, negative predictive value