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Table 2 Changes in blood flow classification, volume, VRR and elasticity score of the lesions after treatment

From: Clinical application of ultrasound-guided percutaneous microwave ablation for benign breast lesions: a prospective study

Variable* Before treatment 1 month 3 months 6 months 12 months 18 months P value***
Blood flow classification** (n = 725) (n = 528) (n = 363) (n = 306) (n = 291) (n = 175)  
No flow 588 (81.1%) 492 (93.2%) 346 (95.3%) 294 (96.1%) 279 (95.9%) 171 (97.7%) < 0.001
Minimal 121 (16.7%) 33 (6.3%) 16 (4.4%) 11 (3.6%) 11 (3.8%) 4 (2.3%)
Moderate 15 (2.1%) 2 (0.4%) 1 (0.3%) 1 (0.3%) 1 (0.3%) 0 (0.0%)
Marked 1 (0.1%) 1 (0.2%) 0 (0.0%) 0 (0.0% 0 (0.0%) 0 (0.0%)
  (n = 725) (n = 529) (n = 367) (n = 311) (n = 291) (n = 185)  
Volume 157.0 (62.8–376.8) 146.5 (47.1–329.7) 100.5 (31.4–301.4) 78.5 (0.0–235.5) 0.0 (0.0–150.7) 0.0 (0.0–0.0) < 0.001
VRR 0.2 (− 0.6–0.6) 0.4 (−0.2–0.8) 0.7 (0.1–1.0) 1.0 (0.5–1.0) 1.0 (1.0–1.0) < 0.001
Disappearance rate 36 (6.8%) 47 (12.8%) 82 (26.4%) 151 (51.9%) 172 (93.0%) < 0.001
Elasticity score (n = 143) (n = 147) (n = 105) (n = 90) (n = 36) (n = 0)  
1 12 (8.4%) 3 (2.0%) 5 (4.8%) 0 (0.0%) 1 (2.8%) 0.003
2 92 (64.3%) 79 (53.7%) 48 (45.7%) 65 (72.2%) 19 (52.8%)
3 38 (26.6%) 59 (40.1%) 48 (45.7%) 24 (26.7%) 16 (44.4%)
4 1 (0.7%) 4 (2.7%) 3 (2.9%) 1 (1.1%) 0 (0.0%)
5 0 (0.0%) 2 (1.4%) 1 (1.0%) 0 (0.0%) 0 (0.0%)
  1. VRR: Volume Reduction Ratio
  2. * Qualitative variables are summarized as frequency (percent) and quantitative variables are summarized as median (25th percentile – 75th percentile)
  3. ** Blood flow classification in this table is assessed by Color Doppler Flow Imaging (CDFI)
  4. *** Chi-squared test and Kruskal Wallis test were used for qualitative and quantitative variables, respectively. P values represent the significance of differences in the assessed variables between different follow ups without taking the temporal relations into account
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