Table 2 Changes in blood flow classification, volume, VRR and elasticity score of the lesions after treatment
Variable* | Before treatment | 1 month | 3 months | 6 months | 12 months | 18 months | P value*** |
|---|---|---|---|---|---|---|---|
Blood flow classification** | (n = 725) | (n = 528) | (n = 363) | (n = 306) | (n = 291) | (n = 175) |  |
No flow | 588 (81.1%) | 492 (93.2%) | 346 (95.3%) | 294 (96.1%) | 279 (95.9%) | 171 (97.7%) | < 0.001 |
Minimal | 121 (16.7%) | 33 (6.3%) | 16 (4.4%) | 11 (3.6%) | 11 (3.8%) | 4 (2.3%) | |
Moderate | 15 (2.1%) | 2 (0.4%) | 1 (0.3%) | 1 (0.3%) | 1 (0.3%) | 0 (0.0%) | |
Marked | 1 (0.1%) | 1 (0.2%) | 0 (0.0%) | 0 (0.0% | 0 (0.0%) | 0 (0.0%) | |
|  | (n = 725) | (n = 529) | (n = 367) | (n = 311) | (n = 291) | (n = 185) |  |
Volume | 157.0 (62.8–376.8) | 146.5 (47.1–329.7) | 100.5 (31.4–301.4) | 78.5 (0.0–235.5) | 0.0 (0.0–150.7) | 0.0 (0.0–0.0) | < 0.001 |
VRR | – | 0.2 (− 0.6–0.6) | 0.4 (−0.2–0.8) | 0.7 (0.1–1.0) | 1.0 (0.5–1.0) | 1.0 (1.0–1.0) | < 0.001 |
Disappearance rate | – | 36 (6.8%) | 47 (12.8%) | 82 (26.4%) | 151 (51.9%) | 172 (93.0%) | < 0.001 |
Elasticity score | (n = 143) | (n = 147) | (n = 105) | (n = 90) | (n = 36) | (n = 0) |  |
1 | 12 (8.4%) | 3 (2.0%) | 5 (4.8%) | 0 (0.0%) | 1 (2.8%) | – | 0.003 |
2 | 92 (64.3%) | 79 (53.7%) | 48 (45.7%) | 65 (72.2%) | 19 (52.8%) | – | |
3 | 38 (26.6%) | 59 (40.1%) | 48 (45.7%) | 24 (26.7%) | 16 (44.4%) | – | |
4 | 1 (0.7%) | 4 (2.7%) | 3 (2.9%) | 1 (1.1%) | 0 (0.0%) | – | |
5 | 0 (0.0%) | 2 (1.4%) | 1 (1.0%) | 0 (0.0%) | 0 (0.0%) | – |