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Table 2 Effect of velogenic viscerotropic (VVNDV) AF2240 and tamoxifen in mortality rate, body and tumour weight of mice

From: Regression of solid breast tumours in mice by Newcastle disease virus is associated with production of apoptosis related-cytokines

Group Animal number Body weight ± SD Tumour weight (g) Inhibition
(%)
Beginning End Mortality rate (%) Beginning End
CC 6 6 0 16.66 ± 0.70 21.26 ± 1.24 * 1.45 ± 0.43
CT 6 6 0 16.48 ± 0.09 20.88 ± 0.79 * 1.21 ± 0.41 16.55
CNDV
 8HA NDV 6 6 0 16.77 ± 0.11 19.49 ± 0.30 * NG # 100
 16HA NDV 6 6 0 16.64 ± 0.32 19.30 ± 0.06 * NG # 100
 32HA NDV 6 6 0 16.86 ± 0.10 19.45 ± 0.10 * NG # 100
 64HA NDV 6 6 0 16.54 ± 0.31 19.66 ± 0.13 * NG # 100
CNDV + T
 8HA NDV 6 6 0 16.93 ± 0.41 19.33 ± 0.16 * NG # 100
 16HA NDV 6 6 0 16.86 ± 0.14 19.50 ± 0.30 * NG # 100
 32HA NDV 6 6 0 16.87 ± 0.06 21.00 ± 0.40 * 2.27 ± 0.28# −56.55
 64HA NDV 6 6 0 16.66 ± 0.06 20.59 ± 0.36 * 3.64 ± 0.23# −151.03
  1. Results expressed in mean ± S.D. *p < 0.05 compared with beginning body weight; #p < 0.05 compared with cancer control (CC). CT, allotransplanted + tamoxifen; CNDV, allotransplanted + virus; CNDV+T, allotransplanted + virus + Tamoxifen; NG, negative