Table 3 Univariate and multivariate analyses for progression-free and overall survival using the Cox proportional hazard model

 <55

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 ≥55

0.99 (0.67–1.44) 0.939

1.33 (0.80–2.20) 0.268

1.14 (0.67–1.92) 0.634

1.51 (0.75–3.04) 0.245

 1–2

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 3–4

2.29 (1.37–3.84) 0.002

2.38 (1.26–4.51) 0.008

3.12 (1.64–5.90) < 0.001

3.24 (1.54–6.82) 0.009

 ≤800

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 >800

1.04 (0.71–1.53) 0.826

1.14 (0.69–1.90) 0.605

0.79 (0.47–1.34) 0.382

0.93 (0.45–1.91) 0.838

 III

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 IV

0.91 (0.62–1.33) 0.629

0.74 (0.47–1.18) 0.210

0.75 (0.44–1.26) 0.277

0.62 (0.32–1.24) 0.177

 Others

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 Mucinous

2.64 (1.54–4.50) < 0.001

2.31 (1.26–4.24) 0.007

4.69 (2.48–8.85) < 0.001

3.24 (1.54–6.82) 0.002

 Clear cell

2.10 (1.30–3.42) 0.003

1.92 (1.12–3.29) 0.017

2.62 (1.37–4.99) 0.004

2.56 (1.21–5.30) 0.013

 ≤1 cm

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 >1 cm

2.86 (1.75–4.66) < 0.001

2.40 (1.43–4.04) 0.001

3.46 (1.89–6.33) < 0.001

2.43 (1.28–4.63) 0.007

 Standard

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 Radical

0.94 (0.64–1.39) 0.771

1.75 (1.02–2.99) 0.042

0.98 (0.57–1.67) 0.933

1.86 (0.97–3.56) 0.062

 No

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 Yes

0.67 (0.17–2.76) 0.004

0.33 (0.18–0.61) < 0.001

0.36 (0.09–1.49) 0.002

0.32 (0.16–0.62) 0.001

 No

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

1.00 (Reference)

 Yes

1.03 (0.25–4.26) 0.074

2.89 (1.65–5.07) < 0.001

0.46 (0.11–1.97) 0.553

1.78 (0.74–4.32) 0.201