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Fig. 6 | BMC Cancer

Fig. 6

From: Reduced FRG1 expression promotes prostate cancer progression and affects prostate cancer cell migration and invasion

Fig. 6

Reduced FRG1 expression enhances p38 MAPK phosphorylation: a. Panel of blots showing enhanced p38 MAPK phosphorylation with FRG1 knockdown in DU145 cells but no change in activation of ERK levels. b. Panel of blots showing enhanced p38 MAPK phosphorylation with FRG1 knockdown in PC3 cells but mild change in phospho ERK levels. si represents protein lysate from FRG1 knockdown cells and sc represents cells expressing scrambled vector control. c. Panel of blot shows neutralization of p38 activation, when FRG1 depletion is rescued by transfection with FRG1 expression vector, in DU145 cells d. Panel of blot shows neutralization of p38 activation, when FRG1 depletion is rescued by transfection with FRG1 expression vector, in PC3 cells. All the experiments were repeated three times

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