| |
Person-years
|
No. of cases
|
Incidence rate (per 100 person-years)
|
Crude HR (95% CI)
|
Model 1 HR (95% CI)
|
Model 2 HR (95% CI)
|
Model 3 HR (95% CI)
|
|---|
|
Late presentation
|
954.1
|
274
|
28.7
|
2.08 (1.69, 2.56)
|
1.99 (1.61, 2.46)
|
1.94 (1.57. 2.41)
|
1.76 (1.42. 2.18)
|
|
Irregular visits
|
1346.7
|
283
|
21.0
|
1.52 (1.24, 1.86)
|
1.49 (1.21, 1.82)
|
1.44 (1.17, 1.76)
|
1.31 (1.06, 1.61)
|
|
Regular visits
|
933.3
|
128
|
13.7
|
Reference
|
Reference
|
Reference
|
Reference
|
|
p value
| | | |
<.001
|
<.001
|
<.001
|
<.001
|
- HR hazard ratio, CI confidence interval.
- *HRs were obtained from Cox models with hospital as a stratification factor.
- Model 1: Adjusted for sex, age ((≥ 40 – < 50, ≥ 50 – < 60, and ≥ 60 years), and year of HCC diagnosis.
- Model 2: Further adjusted for income percentile (≤ 30th, > 30th – ≤ 70th, and > 70th), and residential area (metropolitan and rural).
- Model 3: Further adjusted for initial treatment (liver transplantation, resection, radiofrequency ablation, transarterial chemoembolization, other and no treatment)
