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Table 3 Hazard ratios (95% confidence intervals) for all-cause mortality in patients with newly diagnosed hepatocellular carcinoma by hepatitis B presentation group

From: Late presentation of hepatitis B among patients with newly diagnosed hepatocellular carcinoma: a national cohort study

  Person-years No. of cases Incidence rate (per 100 person-years) Crude HR (95% CI) Model 1 HR (95% CI) Model 2 HR (95% CI) Model 3 HR (95% CI)
Late presentation 954.1 274 28.7 2.08 (1.69, 2.56) 1.99 (1.61, 2.46) 1.94 (1.57. 2.41) 1.76 (1.42. 2.18)
Irregular visits 1346.7 283 21.0 1.52 (1.24, 1.86) 1.49 (1.21, 1.82) 1.44 (1.17, 1.76) 1.31 (1.06, 1.61)
Regular visits 933.3 128 13.7 Reference Reference Reference Reference
p value     <.001 <.001 <.001 <.001
  1. HR hazard ratio, CI confidence interval.
  2. *HRs were obtained from Cox models with hospital as a stratification factor.
  3. Model 1: Adjusted for sex, age ((≥ 40 – < 50, ≥ 50 – < 60, and ≥ 60 years), and year of HCC diagnosis.
  4. Model 2: Further adjusted for income percentile (≤ 30th, > 30th – ≤ 70th, and > 70th), and residential area (metropolitan and rural).
  5. Model 3: Further adjusted for initial treatment (liver transplantation, resection, radiofrequency ablation, transarterial chemoembolization, other and no treatment)