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Fig. 3 | BMC Cancer

Fig. 3

From: Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels

Fig. 3

Ascorbate levels in breast tumor tissue and adjacent normal tissue. a There was no difference in the range of levels of ascorbate measured in tumor or normal breast tissue samples. b There was no association between tumor (n = 49) and normal (n = 49) breast tissue ascorbate levels. c Ascorbate levels were significantly lower in grade 2 (n = 20) or 3 (n = 22) tumors than in grade 1 (n = 9). d Ascorbate levels were lower in tumors with necrosis (n = 27) than in those without (n = 23). Means ± S.D. are shown

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