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Table 5 Bivariate analysis with Cox proportional hazard model

From: Locally advanced breast cancer treated with neoadjuvant chemotherapy and adjuvant radiotherapy: a retrospective cohort analysis

   Local recurrence Recurrence-free survival
Variable   Hazard ratio 95% CI p-value Hazard ratio 95% CI p-value
Nottigham grade 2 vs. 3 0.30 0.05–1.81 0.43 0.67 0.24–1.88 0.75
Menopausal status Post vs. pre 0.25 0.03–2.10 0.44 1.32 0.57–3.06 0.81
LVI No vs. Yes 0.69 0.15–3.08 0.63 0.48 0.19–1.22 0.12
Pathological nodal status No vs. yes 1.33 0.16–11.03 0.79 0.41 0.05–3.05 0.38
Tumour size before surgery   1.09 0.86–1.38 0.47 1.24 1.08–1.42 0.003
Tumour size at surgery   1.03 0.85–1.24 0.77 1.18 1.09–1.29 < 0.001
Miller-Payne score   0.74 0.42–1.32 0.31 0.56 0.4–0.8 0.001
Chevallier score   0.96 0.46–2.02 0.92 2.01 1.14–3.53 0.015
Standard pathology response     0.51    0.05
  NR vs. pCR 3.98 0.36–44.0   13.29 1.6–110.5  
  PR vs. pCR 2.07 0.24–17.7   7.43 0.99–56.1  
Pretreatment stage group     0.51    0.05
  II vs. III 0.62 0.15–2.61   0.41 0.17–1.0  
  1. Abbreviations: CI confidence interval, LVI lymphovascular invasion, NR no response, pCR pathological complete response, PR partial response