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Table 2 Summary of study visits, procedures, and evaluations

From: Systemic and tumor-directed therapy for oligometastatic prostate cancer: study protocol for a phase II trial for veterans with de novo oligometastatic disease

 

At inclusion

Day 1

Between day 30–60

At 6 months

Monthly for first 12 months

Every 3 months thereafter

NaF- or PSMA- PET CT (with CT of chest/abdomen/pelvis)

x

     

PSA, total testosterone

x

   

x

x

Radical prostatectomy

 

x

    

SBRT to all sites of metastases

  

x

   

Prostate bed/nodes RT a

      

Lupron depot (6 month)b

 

x

    

Start apalutamide, abiraterone acetate, prednisone b

 

x

    

Stop apalutamide, abiraterone acetate, taper prednisone

   

x

  

Quality-of-life and toxicity assessments

x

   

x

x

  1. aif indicated, This pelvic RT can extend beyond or be completed after ADT
  2. bwithin 3 days of surgery