Table 2 Independent predictors of survival from a multivariate Cox proportional hazards model at the first and second rounds of TACE

Male gender

1.09 (0.86–1.38)

–

–

Tumor size (cm)

< 0.001

 ≤7

1

1

 >7

1.90 (1.53–2.36)

1.91 (1.36–2.69)

Tumor number

< 0.001

 Unifocal

1

1

 Multifocal

1.73 (1.43–2.09)

1.78 (1.45–2.19)

Alpha-fetoprotein (ng/mL)

< 0.001

 ≤400

1

1

 >400

1.58 (1.27–1.95)

2.31 (1.63–3.28)

Total bilirubin (mg/dL)

0.241

 ≤0.9

1

1

 >0.9

1.31 (1.08–1.58)

1.14 (0.91–1.43)

Serum albumin (g/dL)

0.004

 ≥3.6

1

1

 <3.6

1.45 (1.19–1.77)

1.39 (1.11–1.75)