| All (n = 2039) | No antihypertensive use (n = 614) | Any antihypertensive use (n = 1425) | |||
---|---|---|---|---|---|---|
n | (%) | n | (%) | n | (%) | |
Year of colon cancer diagnosis | ||||||
 1995–1999 | 410 | (20.1) | 105 | (17.1) | 305 | (21.4) |
 2000–2004 | 569 | (27.9) | 157 | (25.6) | 412 | (28.9) |
 2005–2009 | 579 | (28.4) | 171 | (27.9) | 408 | (28.6) |
 2010–2014 | 481 | (23.6) | 181 | (29.5) | 300 | (21.1) |
Age at diagnosis (years) | ||||||
 mean (SD) | 69.9 | (11.6) | 65.8 | (12.7) | 71.6 | (10.6) |
  < 50 | 94 | (4.6) | 59 | (9.6) | 35 | (2.5) |
 50–59 | 294 | (14.4) | 136 | (22.1) | 158 | (11.1) |
 60–69 | 530 | (26.0) | 165 | (26.9) | 365 | (25.6) |
 70–79 | 677 | (33.2) | 162 | (26.4) | 515 | (36.1) |
 80+ | 444 | (21.8) | 92 | (15.0) | 352 | (24.7) |
Sex | ||||||
 Female | 1066 | (52.3) | 323 | (52.6) | 743 | (52.1) |
 Male | 973 | (47.7) | 291 | (47.4) | 682 | (47.9) |
Hispanic ethnicity | ||||||
 Not Hispanic | 1742 | (85.4) | 513 | (83.6) | 1229 | (86.2) |
 Hispanic | 93 | (4.6) | 29 | (4.7) | 64 | (4.5) |
 Unknowna | 204 | (10.0) | 72 | (11.7) | 132 | (9.3) |
Race | ||||||
 White | 1582 | (77.6) | 467 | (76.1) | 1115 | (78.2) |
 Black | 70 | (3.4) | 15 | (2.4) | 55 | (3.9) |
 Asian | 66 | (3.2) | 23 | (3.7) | 43 | (3.0) |
 American Indian/Alaska Native | 9 | (0.4) | 1 | (0.2) | 8 | (0.6) |
 Hawaiian/Pacific Islander | 5 | (0.2) | 2 | (0.3) | 3 | (0.2) |
 Multiple race | 19 | (0.9) | 7 | (1.1) | 12 | (0.8) |
 Other/Unknown | 288 | (14.1) | 99 | (16.1) | 189 | (13.3) |
Smoking before diagnosis | ||||||
 Never | 916 | (45.2) | 307 | (50.4) | 609 | (42.9) |
 Ever | 1112 | (54.8) | 302 | (49.6) | 810 | (57.1) |
 Unknown | 11 |  | 5 |  | 6 |  |
Charlson score at diagnosis | ||||||
 mean (SD) | 0.8 | (1.4) | 0.3 | (0.8) | 1.1 | (1.5) |
 0 | 1085 | (53.2) | 453 | (73.8) | 632 | (44.4) |
 1 | 429 | (21.0) | 87 | (14.1) | 342 | (24.0) |
 2 | 184 | (9.0) | 19 | (3.1) | 165 | (11.6) |
 3+ | 225 | (11.0) | 22 | (3.6) | 203 | (14.3) |
 Unknowna | 116 | (5.7) | 33 | (5.4) | 83 | (5.8) |
BMI at diagnosis (kg/m2) | ||||||
 mean (SD) | 27.9 | (5.9) | 26.7 | (5.3) | 28.5 | (6.1) |
 Underweight (< 18.5) | 41 | (2.1) | 17 | (2.9) | 24 | (1.8) |
 Normal (18.5–24.9) | 610 | (31.4) | 223 | (38.4) | 387 | (28.4) |
 Overweight (25–29.9) | 702 | (36.2) | 212 | (36.6) | 490 | (36.0) |
 Obese (30–34.9) | 380 | (19.6) | 90 | (15.5) | 290 | (21.3) |
 Morbidly obese (35+) | 208 | (10.7) | 38 | (6.6) | 170 | (12.5) |
 Unknown | 98 |  | 34 |  | 64 |  |
Diagnoses in the year before colon cancer | ||||||
 Diabetes | 400 | (19.6) | 36 | (5.9) | 364 | (25.5) |
 Hyperlipidemia/hypercholesterolemia | 655 | (32.1) | 128 | (20.8) | 527 | (37.0) |
 Hypertension | 1111 | (54.5) | 106 | (17.3) | 1005 | (70.5) |
Stage at colon cancer diagnosis | ||||||
 I | 911 | (44.7) | 286 | (46.6) | 625 | (43.9) |
 IIA | 935 | (45.9) | 247 | (40.2) | 688 | (48.3) |
 IIB | 117 | (5.7) | 52 | (8.5) | 65 | (4.6) |
 IIIA | 76 | (3.7) | 29 | (4.7) | 47 | (3.3) |
Grade | ||||||
 Grade I | 187 | (9.7) | 48 | (8.4) | 139 | (10.3) |
 Grade II | 1423 | (73.8) | 434 | (75.6) | 989 | (73.0) |
 Grade III | 294 | (15.2) | 84 | (14.6) | 210 | (15.5) |
 Grade IV | 24 | (1.2) | 8 | (1.4) | 16 | (1.2) |
 Unknown, not stated, or N/A | 111 |  | 40 |  | 71 |  |
Cancer treatment received | ||||||
 Chemotherapy | 277 | (13.6) | 112 | (18.2) | 165 | (11.6) |
 Radiation | 30 | (1.5) | 11 | (1.8) | 19 | (1.3) |
Medication use in the year before colon cancer diagnosisb | ||||||
 Any Statin | 542 | (26.6) | 56 | (9.1) | 486 | (34.1) |
 Aspirin | 685 | (34.1) | 120 | (19.9) | 565 | (40.2) |
 Any antihypertensive | 1078 | (52.9) | 51 | (8.3) | 1027 | (72.1) |
  ACE inhibitor | 524 | (25.7) | 15 | (2.4) | 509 | (35.7) |
  Angiotensin receptor blocker | 92 | (4.5) | 1 | (0.2) | 91 | (6.4) |
  Beta blocker | 528 | (25.9) | 16 | (2.6) | 512 | (35.9) |
  Calcium channel blocker | 287 | (14.1) | 10 | (1.6) | 277 | (19.4) |
  Diuretic | 479 | (23.5) | 20 | (3.3) | 459 | (32.2) |
Type of antihypertensive after colon cancer diagnosisb | ||||||
 ACE inhibitor | 878 | (43.1) | 0 | (0) | 878 | (61.6) |
 Angiotensin receptor blocker | 226 | (11.1) | 0 | (0) | 226 | (15.9) |
 Beta blocker | 890 | (43.6) | 0 | (0) | 890 | (62.5) |
 Calcium channel blocker | 559 | (27.4) | 0 | (0) | 559 | (39.2) |
 Diuretic | 713 | (35.0) | 0 | (0) | 713 | (50.0) |