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Table 2 Gender-, age-, and diagnosis-specific relationship between exposure to tobacco and death owing to extrahepatic cholangiocarcinoma

From: Is exposure to tobacco associated with extrahepatic cholangiocarcinoma epidemics? A retrospective proportional mortality study in China

 

Numbers of outcomes

Numbers of persons observed

‰

RR (95% CI)

Model 1

Model 2

Men

 Control

86

11,937

7.2

1.00

1.00

 Passive

14

1122

12.5

1.61 (0.91–1.85)

1.56 (0.88–2.79)

 Active

115

18,162

6.3

0.93 (0.70–1.23)

0.97 (0.73–1.29)

 Passive & Active

39

2820

13.8

1.81 (1.23–2.66)

1.67 (1.14–2.46)

Women

 Control

64

8191

7.8

1.00

1.00

 Passive

84

11,093

7.6

1.08 (0.77–1.50)

1.09 (0.78–1.52)

 Active

16

864

18.5

2.15 (1.23–3.74)

1.96 (1.16–3.43)

 Passive & Active

33

1617

20.4

2.46 (1.61–3.76)

2.56 (1.66–3.94)

30~49 years

 Control

21

6320

3.3

1.00

1.00

 Passive

17

4971

3.4

1.31 (0.58–2.99)

1.49 (0.63–3.43)

 Active

11

6091

1.8

0.52 (0.23–1.16)

0.56 (0.25–1.25)

 Passive & Active

2

456

4.4

0.91 (0.21–3.96)

0.98 (0.22–4.27)

50~69 years

     

 Control

89

8457

10.5

1.00

1.00

 Passive

67

5333

12.6

1.07 (0.75–1.54)

1.07 (0.75–1.54)

 Active

94

8551

11.0

1.23 (0.88–1.71)

1.25 (0.90–1.75)

 Passive & Active

48

2587

18.6

1.75 (1.23–2.49)

1.72 (1.20–2.46)

70~98 years

     

 Control

40

5351

7.5

1.00

1.00

 Passive

14

1911

7.3

1.08 (0.56–2.10)

1.09 (0.56–2.11)

 Active

26

4384

5.9

0.76 (0.45–1.29)

0.77 (0.45–1.30)

 Passive & Active

22

1394

15.8

1.96 (1.16–3.33)

1.84 (1.08–3.13)

Pathology-based

 Control

54

4501

12.0

1.00

1.00

 Passive

45

2971

15.1

1.35 (0.83–2.19)

1.41 (0.87–2.28)

 Active

62

5537

11.2

1.25 (0.82–1.90)

1.26 (0.89–2.07)

 Passive & Active

31

836

37.1

2.50 (1.59–3.93)

2.38 (1.50–3.77)

Non-pathology-based

 Control

96

15,627

6.1

1.00

1.00

 Passive

53

9244

5.7

0.98 (0.67–1.43)

1.00 (0.69–1.46)

 Active

69

13,489

5.1

0.91 (0.65–1.28)

0.96 (0.68–1.35)

 Passive & Active

41

3601

11.4

1.79 (1.23–2.58)

1.72 (1.19–2.50)

Total

 Control

150

20,128

7.5

1.00

1.00

 Passive

98

12,215

8.0

1.15 (0.86–1.53)

1.15 (0.86–1.55)

 Active

131

19,026

6.9

1.08 (0.83–1.41)

1.11 (0.85–1.44)

 Passive & active

72

4437

16.2

2.06 (1.55–2.73)

1.98 (1.49–2.64)