Table 1 Patient characteristics
Characteristics | N = 151 |
|---|---|
 Age, years | 57 (52–63) |
Sex | |
 Male | 137 (90.7%) |
 Female | 14 (9.3%) |
ECOG performance status | |
 0 | 52 (34.4%) |
 1 | 97 (64.2%) |
 2 | 2 (1.3%) |
Etiology | |
 Hepatitis B | 134 (88.7%) |
 Hepatitis C | 4 (2.6%) |
 Alcohol | 7 (4.6%) |
 Others | 6 (4.0%) |
Child-Pugh class | |
 A | 140 (92.7%) |
 B | 11 (7.3%) |
BCLC stage | |
 B | 5 (3.3%) |
 C | 146 (96.7%) |
Macrovascular invasion | |
 Yes | 63 (41.7%) |
 No | 88 (58.3%) |
No. of extrahepatic spread organ sites | |
 0 | 15 (9.9%) |
 1 | 79 (52.3%) |
 2 | 41 (27.2%) |
  ≥ 3 | 16 (10.6%) |
Sites of extrahepatic spread | |
 Lymph node | 64 (42.4%) |
 Lung | 77 (51.0%) |
 Bone | 32 (21.2%) |
 Peritoneum | 23 (15.2%) |
 Adrenal gland | 13 (8.6%) |
AFP (ng/mL) | |
  < 20 | 41 (27.1%) |
 20–200 | 32 (21.2%) |
  > 200 | 77 (51.0%) |
 Not available | 1 (0.7%) |
 Platelet count (× 103/mm3) | 122.0 (85.0–165.0) |
 Prothrombin time (INR) | 1.08 (1.02–1.16) |
 Albumin (g/dL) | 3.7 (3.4–4.0) |
 Total bilirubin (mg/dL) | 0.7 (0.5–1.0) |
 AST (IU/L) | 39 (28–58) |
 ALT (IU/L) | 26 (18–39) |
Previous therapy | |
 No | 10 (6.6%) |
 Yes | 141 (93.4%) |
 Surgical resection | 69 (45.7%) |
 RFA | 37 (24.5%) |
 TACE | 118 (78.1%) |
 Radiotherapy | 79 (52.3%) |
 Liver transplantation | 12 (7.9%) |