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Table 4 Univariate and multivariate Cox regression analyses of SLC2A3 expression and the clinicopathological factors in the discovery set (TCGA COADREAD cohort)

From: Upregulation of SLC2A3 gene and prognosis in colorectal carcinoma: analysis of TCGA data

 

Overall survival

Disease-free survival

HR(95% CI of HR)

P valuea

HR(95% CI of HR)

P valuea

SLC2A3 low

1.00 (Reference)

 

1.00 (Reference)

 

 UVA SLC2A3 high

1.93 (1.21–3.07)

0.005

2.20 (1.32–3.68)

0.003

 MVA SLC2A3 high

1.98 (1.24–3.17)

0.004

1.85 (1.10–3.12)

0.020

Age < = 65

1.00 (Reference)

   

 Age > 65

2.61 (1.59–4.28)

< 0.001

  

AJCC stage I, II

1.00 (Reference)

 

1.00 (Reference)

 

 AJCC stage III, IV

3.17 (1.96–5.11)

< 0.001

2.48 (1.58–3.89)

< 0.001

  1. Abbreviations: HR hazard ratio, CI confidence interval, UVA univariate, MVA multivariate
  2. aCalculated using the Wald test