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Table 4 Univariate and multivariate Cox regression analyses of SLC2A3 expression and the clinicopathological factors in the discovery set (TCGA COADREAD cohort)

From: Upregulation of SLC2A3 gene and prognosis in colorectal carcinoma: analysis of TCGA data

  Overall survival Disease-free survival
HR(95% CI of HR) P valuea HR(95% CI of HR) P valuea
SLC2A3 low 1.00 (Reference)   1.00 (Reference)  
 UVA SLC2A3 high 1.93 (1.21–3.07) 0.005 2.20 (1.32–3.68) 0.003
 MVA SLC2A3 high 1.98 (1.24–3.17) 0.004 1.85 (1.10–3.12) 0.020
Age < = 65 1.00 (Reference)    
 Age > 65 2.61 (1.59–4.28) < 0.001   
AJCC stage I, II 1.00 (Reference)   1.00 (Reference)  
 AJCC stage III, IV 3.17 (1.96–5.11) < 0.001 2.48 (1.58–3.89) < 0.001
  1. Abbreviations: HR hazard ratio, CI confidence interval, UVA univariate, MVA multivariate
  2. aCalculated using the Wald test