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Table 7 Summary of results obtained at the gene level

From: Genome sequencing analysis of blood cells identifies germline haplotypes strongly associated with drug resistance in osteosarcoma patients

(a) List of 26 common genes from overlapping haplotypes associated with relapse

(b) List of 10 dbSNP ids common to the two datasets amongst the overlapping haplotypes associated with relapse

(c) Genes from targeted DMET analysis associated with both tumor necrosis and overall survival

7SK

rs7071768 (MKI67)

SLC22A8

AKR1D1

rs11016073 (MKI67)

SLC22A1

CACNA2D4

rs61738284 (MKI67)

UGT2B15

CDH13

rs11591817 (MKI67)

CHST12

CDH9

rs10735005 (CACNA2D4)

 

CDRT15

rs3217046 (SLC13A2)

 

CSMD1

rs11568466 (SLC13A2)

 

DGCR6*

rs9890678 (SLC13A2)

 

DQ576041

rs10573756 (PPP1R12C)

 

DQ600701 (also known as PIR61811) *

rs34521018 (PPP1R12C)

 

DQ786190

  

GABRG3

  

HBE1

  

LOC643401

  

MALDR1 (also known as C10orf112) *

  

MKI67

  

OCA2

  

OR51B5

  

PCGF2

  

PDZD4 *

  

PIK3R1 *

  

PKHD1

  

PPP1R12C*

  

SLC13A2*

  

ZNF321P

  

ZNF816

  
  1. Genes marked with * indicate the most frequent haplotypes associated with relapse