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Table 4 Pathways enriched from the 26 genes common to TARGET and INOVA haplotypes

From: Genome sequencing analysis of blood cells identifies germline haplotypes strongly associated with drug resistance in osteosarcoma patients

Pathway name #Entities found #Entities total Entities P value Entities FDR Submitted entities found
Adherens junctions interactions 2 35 0.003 0.228 CDH13; CDH9
Cell-Cell communication 3 133 0.003 0.228 CDH13; PIK3R1; CDH9
Factors involved in megakaryocyte development and platelet production 3 179 0.007 0.228 HBE1
Cell-cell junction organization 2 67 0.009 0.228 CDH13; CDH9
Cell junction organization 2 94 0.017 0.228 CDH13; CDH9
Sodium-coupled sulphate, di- and tri-carboxylate transporters 1 9 0.019 0.228 SLC13A2
MET activates PI3K/AKT signaling 1 10 0.021 0.228 PIK3R1
GP1b-IX-V activation signaling 1 12 0.025 0.228 PIK3R1
PI3K events in ERBB4 signaling 1 15 0.032 0.228 PIK3R1
GABA A receptor activation 1 15 0.032 0.228 GABRG3
Signaling by FGFR3 fusions in cancer 1 16 0.034 0.228 PIK3R1
Erythrocytes take up oxygen and release carbon dioxide 1 16 0.034 0.228 HBE1
Signaling by FGFR4 in disease 1 18 0.038 0.228 PIK3R1
PI3K events in ERBB2 signaling 1 22 0.046 0.228 PIK3R1
Tie2 Signaling 1 22 0.046 0.228 PIK3R1