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Table 4 Pathways enriched from the 26 genes common to TARGET and INOVA haplotypes

From: Genome sequencing analysis of blood cells identifies germline haplotypes strongly associated with drug resistance in osteosarcoma patients

Pathway name

#Entities found

#Entities total

Entities P value

Entities FDR

Submitted entities found

Adherens junctions interactions

2

35

0.003

0.228

CDH13; CDH9

Cell-Cell communication

3

133

0.003

0.228

CDH13; PIK3R1; CDH9

Factors involved in megakaryocyte development and platelet production

3

179

0.007

0.228

HBE1

Cell-cell junction organization

2

67

0.009

0.228

CDH13; CDH9

Cell junction organization

2

94

0.017

0.228

CDH13; CDH9

Sodium-coupled sulphate, di- and tri-carboxylate transporters

1

9

0.019

0.228

SLC13A2

MET activates PI3K/AKT signaling

1

10

0.021

0.228

PIK3R1

GP1b-IX-V activation signaling

1

12

0.025

0.228

PIK3R1

PI3K events in ERBB4 signaling

1

15

0.032

0.228

PIK3R1

GABA A receptor activation

1

15

0.032

0.228

GABRG3

Signaling by FGFR3 fusions in cancer

1

16

0.034

0.228

PIK3R1

Erythrocytes take up oxygen and release carbon dioxide

1

16

0.034

0.228

HBE1

Signaling by FGFR4 in disease

1

18

0.038

0.228

PIK3R1

PI3K events in ERBB2 signaling

1

22

0.046

0.228

PIK3R1

Tie2 Signaling

1

22

0.046

0.228

PIK3R1