Prognostic factors | Univariable analysis | Multivariable analysis | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age | 0.818 | 0.361 | ||
<60 | 1.161 (0.575–2.344) | 1.328 (0.722–2.442) | ||
≥60 | 1 | 1 | ||
Gender | 0.287 | 0.063 | ||
Male | 1.375 (0.545–3.470) | 0.511 (0.252–1.036) | ||
Female | 1 | 1 | ||
Primary tumor Grade | 0.0028 | 0.293 | ||
G1 | 0.502 (0.144–0.756) | 0.51 (0.147–1.782) | ||
G2 | 1 | 1 | ||
Hepatic Tumor Number | 0.000 | 0.000 | ||
Single | 0.17 (0.123–0.214) | 0.07 (0.023–0.214) | ||
Multiple | 1 | 1 | ||
Lymph-node meta | 0.035 | 0.374 | ||
Present | 1.057 (0.393–2.839) | 0.988 (0.371–2.629) | ||
Absent | 1 | 1 | ||
Tumor origin | 0.273 | 0.329 | ||
Pancreas | 0.490 (0.139–1.732) | 1.463 (0.682–3.138) | ||
GI tract | 1 | 1 | ||
Treatment modality | 0.009 | 0.045 | ||
Local treatment | 0.817 (0.690–0.917) | 0.801 (0.684–0.887) | ||
Systemic treatment | 0.921 (0.702–0.998) | 0.922 (0.781–0.998) | ||
Combined treatment | 1 | 1 | ||
Elevation of ki67 index | 0.022 | 0.027 | ||
Yes | 1.997 (1.018–3.547) | 1.396 (1.174–3.483) | ||
No | 1 | 1 | ||
Longest hepatic tumor diameter | 0.343 | 0.775 | ||
> 4.5 | 0.644 (0.2–2.072) | 0.875 (0.352–2.175) | ||
<=4.5 | 1 | 1 |