Skip to main content

Table 3 Univariable and multivariable analyses of metastatic survival duration in 108 patients

From: Risk factors affecting prognosis in metachronous liver metastases from WHO classification G1 and G2 gastroenteropancreatic neuroendocrine tumors after initial R0 surgical resection

Prognostic factors

Univariable analysis

Multivariable analysis

 

HR (95% CI)

P-value

HR (95% CI)

P-value

Age

 

0.818

 

0.361

 <60

1.161 (0.575–2.344)

 

1.328 (0.722–2.442)

 

 ≥60

1

 

1

 

Gender

 

0.287

 

0.063

 Male

1.375 (0.545–3.470)

 

0.511 (0.252–1.036)

 

 Female

1

 

1

 

Primary tumor Grade

 

0.0028

 

0.293

 G1

0.502 (0.144–0.756)

 

0.51 (0.147–1.782)

 

 G2

1

 

1

 

Hepatic Tumor Number

 

0.000

 

0.000

 Single

0.17 (0.123–0.214)

 

0.07 (0.023–0.214)

 

 Multiple

1

 

1

 

Lymph-node meta

 

0.035

 

0.374

 Present

1.057 (0.393–2.839)

 

0.988 (0.371–2.629)

 

 Absent

1

 

1

 

Tumor origin

 

0.273

 

0.329

 Pancreas

0.490 (0.139–1.732)

 

1.463 (0.682–3.138)

 

 GI tract

1

 

1

 

Treatment modality

 

0.009

 

0.045

 Local treatment

0.817 (0.690–0.917)

 

0.801 (0.684–0.887)

 

 Systemic treatment

0.921 (0.702–0.998)

 

0.922 (0.781–0.998)

 

 Combined treatment

1

 

1

 

Elevation of ki67 index

 

0.022

 

0.027

 Yes

1.997 (1.018–3.547)

 

1.396 (1.174–3.483)

 

 No

1

 

1

 

Longest hepatic tumor diameter

 

0.343

 

0.775

 > 4.5

0.644 (0.2–2.072)

 

0.875 (0.352–2.175)

 

 <=4.5

1

 

1