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Table 6 Cox proportional hazard analysis for sex difference in relationship to overall survival in various clinical subgroups (Male = 1)

From: Is there a sex difference in postoperative prognosis of hepatocellular carcinoma?

   No. of patients HR 95% CI P
Overall   516 0.881 0.513 – 1.513 0.646
Age, years <58 262 1.671 0.590 – 4.735 0.334
≥58 254 0.567 0.279 – 1.152 0.117
Anti-HCV Negative 381 0.892 0.468 – 1.701 0.729
Positive 135 0.813 0.288 – 2.291 0.695
HBsAg Negative 157 0.556 0.236 – 1.309 0.179
Positive 359 1.244 0.580 – 2.669 0.575
Liver cirrhosis No 219 1.573 0.602 – 4.111 0.356
Yes 297 0.625 0.318 – 1.228 0.172
Microvascular invasion No 343 0.830 0.420 – 1.641 0.593
Yes 173 0.751 0.304 – 1.854 0.535
Macrovascular invasion No 449 0.924 0.502 – 1.699 0.798
Yes 67 0.629 0.189 – 2.102 0.452
Histology grade <3 233 1.005 0.403 – 2.509 0.991
≥3 283 0.831 0.424 – 1.630 0.590
Capsule No 141 0.621 0.231 – 1.617 0.322
Yes 375 0.987 0.512 – 1.903 0.970
Tumor number 1 306 0.671 0.344 – 1.306 0.240
>1 210 1.349 0.512 – 3.555 0.545
Ascites No 477 0.880 0.487 – 1.591 0.672
Yes 39 0.965 0.254 – 3.662 0.958
Alcoholism No 383 0.768 0.426 – 1.385 0.381
Yes 133 20.814 0.000 - 29575628 0.675
Largest tumor size, cm ≤4 242 0.609 0.252 – 1.470 0.270
>4 274 1.023 0.507 – 2.062 0.950
AFP, ng/mL ≤35 270 1.003 0.374 – 2.689 0.996
>35 246 0.968 0.504 – 1.858 0.923
Albumin, g/L ≤4 279 1.064 0.519 – 2.180 0.866
>4 237 0.658 0.288 – 1.504 0.321
Bilirubin, mg/dL ≤0.8 263 0.674 0.327 – 1.390 0.285
>0.8 253 1.129 0.469 – 2.721 0.786
PT, sec <12 259 0.455 0.213 – 0.972 0.042
≥12 257 1.61 0.671 – 3.819 0.289
PT, INR <1.1 270 0.438 0.205 – 0.936 0.033
≥1.1 246 1.677 0.703 – 4.001 0.243
Creatinine, mg/dL ≤1 294 1.122 0.590 – 2.136 0.725
>1 222 0.445 0.152 – 1.301 0.139
AST, U/L ≤39 262 0.836 0.370 – 1.889 0.667
>39 254 0.931 0.452 – 1.920 0.847
ALT, U/L ≤40 255 0.790 0.390 – 1.597 0.511
>40 261 1.092 0.451 – 2.647 0.845
  1. AFP alpha-fetoprotein, PT prothrombin time, INR international normalized ratio, AST aspartate aminotransferase, ALT alanine aminotransferase, HR hazard ratio, CI confidence interval; Values in bold, P < 0.05