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Table 2 Competing risk analyses of factors associated with cancer recurrence after surgery for breast cancer

From: Single dose of dexamethasone is not associated with postoperative recurrence and mortality in breast cancer patients: a propensity-matched cohort study

Variables

Univariate

Multivariate

HR

95% CI

P-value

HR

95% CI

P-value

Dexamethasone

 No

1 (ref)

   

1 (ref)

   

 Yes

1.348

0.912

1.994

0.134

1.442

0.969

2.145

0.071

Age

0.989

0.976

1.002

0.089

    

Age (years)

 < 40

1 (ref)

   

1 (ref)

   

 40–49

0.673

0.469

0.967

0.032

0.866

0.598

1.254

0.447

 50–59

0.705

0.482

1.032

0.072

0.779

0.526

1.154

0.213

 60–69

0.665

0.421

1.05

0.080

0.703

0.416

1.188

0.188

 ≥70

0.563

0.254

1.249

0.158

0.591

0.247

1.414

0.237

BMI

0.99

0.948

1.034

0.654

    

BMI (kg m−2)

 < 18.4

1.033

0.523

2.039

0.927

0.835

0.421

1.658

0.607

 18.4–22.9

1 (ref)

   

1 (ref)

   

 23–24.9

1.026

0.739

1.423

0.880

1.100

0.791

1.530

0.572

 25–29.9

1.033

0.749

1.426

0.842

1.021

0.738

1.411

0.901

 ≥30

0.73

0.298

1.789

0.491

0.626

0.254

1.546

0.310

HTN

 No

1 (ref)

   

1 (ref)

   

 Yes

0.952

0.686

1.322

0.770

1.045

0.714

1.531

0.820

DM

 No

1 (ref)

   

1 (ref)

   

 Yes

1.132

0.700

1.832

0.612

1.158

0.681

1.968

0.588

Anaesthetic agents

 TIVA

1 (ref)

   

1 (ref)

   

 Volatile

1.247

0.550

2.830

0.597

1.072

0.470

2.441

0.869

N2O

 No

1 (ref)

       

 Yes

1.325

0.879

1.997

0.179

    

Transfusion

 No

1 (ref)

       

 Yes

2.591

0.644

10.426

0.180

    

Premedicationa

 No

1 (ref)

       

 Yes

0.878

0.670

1.150

0.345

    

Surgical procedure

 BCS

1 (ref)

   

1 (ref)

   

 Mastectomy

2.516

1.883

3.360

< 0.001

1.934

1.429

2.618

< 0.001

TNM staging

 1

1 (ref)

   

1 (ref)

   

 2

2.397

1.674

3.431

< 0.001

1.778

1.168

2.706

0.007

 3

7.395

5.217

10.48

< 0.001

5.300

3.433

8.183

< 0.001

Oestrogen receptor

 No

1 (ref)

   

1 (ref)

   

 Yes

0.576

0.443

0.748

< 0.001

0.886

0.597

1.315

0.549

Progesterone receptor

 No

1 (ref)

   

1 (ref)

   

 Yes

0.605

0.467

0.783

< 0.001

0.835

0.571

1.222

0.355

Chemotherapy

 No

1 (ref)

   

1 (ref)

   

 Yes

3.265

2.213

4.818

< 0.001

0.958

0.580

1.582

0.866

Radiotherapy

 No

1 (ref)

       

 Yes

1.211

0.917

1.597

0.177

    
  1. CI confidence interval, HR hazard ratio, BMI body mass index, HTN hypertension, DM diabetes mellitus, TIVA total intravenous anaesthesia, N2O nitrous oxide, BCS breast conserving surgery, TNM tumour-node-metastasis
  2. aPremedication: Midazolam 0.03 mg kg−1 was administered
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BMC Cancer

ISSN: 1471-2407

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