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Table 2 Univariate and Multivariate Analysis for DFS and OS in ESCC Patients

From: Increased MET gene copy number negatively affects the survival of esophageal squamous cell carcinoma patients

  DFS OS
P value HR (95% CI) P value HR(95% CI)
Univariate analysis
 Sex 0.251 1.204 (0.877–1.655) 0.125 1.295 (0.931–1.802)
 Age 0.994 1.001 (0.787–1.273) 0.982 0.997 (0.781–1.273)
 Smoking 0.538 1.079 (0.846–1.377) 0.345 1.126 (0.880–1.440)
 Tumor Size 0.166 1.185 (0.932–1.509) 0.113 1.218 (0.954–1.555)
 Tumor Location 0.879 0.984 (0.799–1.212) 0.793 1.029 (0.831–1.274)
 Differentiation 0.047 1.246 (1.003–1.549) 0.080 1.217 (0.977–1.518)
 Vessel invasion < 0.001 1.597 (1.228–2.076) 0.001 1.576 (1.205 2.061)
 Nerve invasion 0.02 1.335 (1.046–1.703) 0.008 1.401 (1.094–1.793)
 Clinical stage < 0.001 2.856 (2.230–3.659) < 0.001 2.899 (2.255–3.727)
MET FISH-positivity 0.001 2.114 (1.378–3.245) 0.002 2.002 (1.293–3.099)
Mutivariate analysis
 Differentiation 0.376 1.106 (0.885–1.381)
 Vessel invasion 0.425 1.119 (0.849–1.474) 0.455 1.113 (0.841–1.472)
 Nerve invasion 0.506 1.089 (0.848–1.398) 0.269 1.153 (0.896–1.485)
 Clinical stage < 0.001 2.672 (2.061–3.465) < 0.001 2.745 (2.111–3.569)
MET FISH-positivity 0.002 1.953 (1.271–2.999) 0.003 1.926 (1.243–2.983)