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Fig. 2 | BMC Cancer

Fig. 2

From: Stromal integrin α11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft tumors

Fig. 2

Tumor cell proliferation. The fraction of Ki67-positive tumor cells in MDA-MB-231 and MDA-MB-468 xenograft tumors (a-c). Reduced percentage of Ki67-positive tumor cells was only seen in MDA-MB-231 mammary fat pad tumors in α11-KO mice compared to WT (n = 7 for MDA-MB-231 and MDA-MB-468 mammary fat pad tumors, and n = 4 WT and n = 5 α11-KO for MDA-MB-231 subcutaneous tumors). Mean ± SD. * p < 0.05. Representative images of Ki67 staining of sections from all xenograft tumors in WT and α11-KO mice (d). Scale bars indicate 100 μm

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