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Fig. 10 | BMC Cancer

Fig. 10

From: Stromal integrin α11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft tumors

Fig. 10

Heterospheroids. The individual interstitial fluid pressures (PIF) in heterospheroids containing a mixture of mouse embryonic fibroblasts (MEFs) and MDA-MB-231 breast tumor cells (4:1) (a). α11-KO MEFs + MDA-MB-231 spheroids showed a significant reduction in PIF compared to WT MEFs + MDA-MB-231 spheroids. *** p < 0.001. Transmission electron microscopy images show collagen fibrils in both heterospheroid types (b)

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