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Table 2 Correlation between risk categories across variables: Negative Percent Agreement (NPA), Positive Percent Agreement (PPA) and Overall Percent Agreement (OPA) for all the variables tested and the 95% CI scores are provided

From: Analytical validation of CanAssist-Breast: an immunohistochemistry based prognostic test for hormone receptor positive breast cancer patients

Parameters

OPA (95% CI)

NPA (95% CI)

PPA (95% CI)

Inter-observer

93.3 (91.2, 94.9)

93.1 (90.3, 95.4)

93.4 (90.2, 95.8)

Intra-observer

91.3 (88.4, 93.7)

91.7 (87.9, 94.6)

90.8 (85.8, 94.4)

Inter-operator

95.2 (89.9, 98.2)

93.3 (83.8, 98.2)

97.0 (89.5, 99.6)

Inter-run

95.3 (90.2, 98.3)

93.8 (82.8, 98.7)

96.3 (89.6, 99.2)

Intra-run/intra-operator

99.2 (95.6, 100.0)

98.3 (91.1, 100.0)

100.0 (94.3, 100.0)

  1. OPA: overall percent agreement, NPA: Negative percent agreement, PPA: Positive percent agreement, CI: confidence Interval
  2. Place holder for Table 2 can be placed in ‘Precision on risk-category prediction’ in “Results” section at line no. 266