Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Correlation between IHC gradings of 5 biomarkers across variables: Intra-class correlation coefficient (ICC) for IHC gradings of all 5 CAB biomarkers tested for inter-observer, intra-observer, inter-operator, inter-run and intra-run variability

From: Analytical validation of CanAssist-Breast: an immunohistochemistry based prognostic test for hormone receptor positive breast cancer patients

Variables Percentage of cells stained Intensity of staining
  CD44 ABCC4 ABCC11 N-Cadherin Pan-Cadherin Pan-Cadherin
Inter-observer 0.98 0.84 0.83 0.79 0.75 0.84
Intra-observer 0.96 0.91 0.91 0.92 0.92 0.81
Inter-operator 0.98 0.97 0.97 0.86 0.90 0.94
Inter-run 0.97 0.93 0.97 0.97 0.95 0.93
Intra-run/Intra-operator 0.99 0.99 0.99 0.99 0.98 0.97
  1. Place holder for Table 1 Can be placed in Inter-observer (pathologist) variability section in “Results” at line no. 221