Skip to main content

Table 1 Comparison of mRNA expression of MCMs in glioma tumor tissue by qRT-PCR and microarray analysis

From: Correction to: Minichromosome Maintenance (MCM) family as potential diagnostic and prognostic tumor markers for human gliomas

Gene

Unique ID

Gene origin

Fold

p value

II/Normal

III/Normal

IV/Normal

III/II

IV/II

IV/III

(II-IV)/Normal

II → Normal

III → Normal

IV → Normal

III → II

IV → II

IV → III

MCM2

202107_s_at

qRT-PCR

1.97

3.98

4.52

2.02

2.29

1.14

3.5

1.59E-02

2.15E-04

3.97E-04

3.80E-03

6.10E-04

8.31E-02

Microarray

1.68

3.74

5.21

2.23

3.10

1.39

3.42E-02

2.98E-05

1.75E-08

8.38E-09

7.03E-06

1.26E-06

MCM3

201555_at

qRT-PCR

1.51

3.35

4.29

2.22

2.84

1.28

3.1

1.37E-02

1.95E-03

2.73E-04

1.89E-02

1.10E-03

1.72E-03

Microarray

1.84

2.62

2.91

1.42

1.58

1.11

4.85E-03

2.66E-05

3.71E-06

1.06E-02

9.77E-07

6.82E-04

MCM4

222036_s_at

qRT-PCR

2.07

4.29

6.68

2.07

3.23

1.56

4.3

6.21E-02

4.36E-02

2.53E-02

7.30E-02

4.26E-02

6.82E-02

Microarray

1.93

2.47

3.93

1.28

2.04

1.59

7.19E-02

1.82E-02

3.68E-03

6.01E-03

2.89E-03

4.29E-03

MCM5

201755_at

qRT-PCR

1.77

3.51

6.05

1.98

3.42

1.72

3.8

1.49E-02

1.38E-03

5.05E-04

1.32E-02

1.67E-03

7.29E-03

Microarray

0.95

1.63

2.89

1.72

3.04

1.77

5.91E-03

2.79E-03

5.81E-03

3.09E-04

8.59E-07

1.23E-03

MCM6

201930_at

qRT-PCR

1.55

3.89

4.95

2.51

3.19

1.27

3.5

3.96E-02

1.05E-02

1.16E-02

2.65E-02

1.17E-02

7.92E-02

Microarray

2.65

2.88

4.75

1.09

1.79

1.65

9.12E-03

1.07E-04

6.77E-04

8.10E-09

5.24E-03

1.42E-03

MCM7

208795_s_at

qRT-PCR

1.53

3.08

4.52

2.01

2.95

1.47

3.0

3.82E-02

2.02E-03

9.81E-03

1.25E-02

1.20E-03

4.01E-03

Microarray

1.31

2.82

3.61

2.15

2.76

1.28

1.59E-04

5.09E-04

3.80E-04

4.79E-08

9.28E-08

6.36E-02

MCM10

220651_s_at

qRT-PCR

2.17

3.59

5.05

1.65

2.33

1.41

3.6

3.90E-02

4.50E-04

1.46E-04

2.96E-02

1.88E-03

2.60E-03

Microarray

6.92

23.87

27.96

3.45

4.04

1.17

1.37E-03

5.39E-08

7.61E-09

5.86E-07

2.59E-09

5.83E-02

  1. MCM3 and MCM5, MCM7 and MCM10 were significant different between grade II, III and IV samples (p < 0.05). MCM2 and MCM6 expressions were significantly increased between grade II (low grade) and III-IV (high grade) samples (p < 0.05)
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us