Table 9 GO analysis of differentially expressed target genes of lncRNAs in lung cancer
Category | Term | Count | % | P-value | False Discovery Rate |
|---|---|---|---|---|---|
GOTERM_BP_DIRECT | GO:0007062~sister chromatid cohesion | 29 | 15.7 | 4.40E-05 | 5.60E-03 |
GOTERM_BP_DIRECT | GO:0000184~nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 15 | 8.1 | 4.80E-12 | 6.70E-09 |
GOTERM_BP_DIRECT | GO:0019083~viral transcription | 15 | 8.1 | 3.50E-11 | 2.50E-08 |
GOTERM_BP_DIRECT | GO:0006614~SRP-dependent cotranslational protein targeting to membrane | 15 | 8.1 | 3.10E-03 | 1.20E-01 |
GOTERM_BP_DIRECT | GO:0006413~translational initiation | 14 | 7.6 | 2.20E-10 | 1.00E-07 |
GOTERM_BP_DIRECT | GO:0051056~regulation of small GTPase mediated signal transduction | 14 | 7.6 | 2.10E-05 | 3.30E-03 |
GOTERM_BP_DIRECT | GO:0006364~rRNA processing | 14 | 7.6 | 1.10E-04 | 1.10E-02 |
GOTERM_BP_DIRECT | GO:0006412~translation | 13 | 7 | 2.80E-08 | 7.80E-06 |
GOTERM_BP_DIRECT | GO:0016032~viral process | 13 | 7 | 3.40E-06 | 6.90E-04 |
GOTERM_BP_DIRECT | GO:0006367~transcription initiation from RNA polymerase II promoter | 13 | 7 | 1.90E-05 | 3.30E-03 |
GOTERM_BP_DIRECT | GO:0007165~signal transduction | 12 | 6.5 | 5.00E-09 | 1.80E-06 |
GOTERM_BP_DIRECT | GO:0000132~establishment of mitotic spindle orientation | 11 | 5.9 | 1.80E-06 | 4.20E-04 |
GOTERM_BP_DIRECT | GO:0051301~cell division | 11 | 5.9 | 5.00E-02 | 5.90E-01 |
GOTERM_BP_DIRECT | GO:0051436~negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 11 | 5.9 | 5.10E-02 | 5.90E-01 |
GOTERM_BP_DIRECT | GO:0043488~regulation of mRNA stability | 11 | 5.9 | 8.50E-02 | 7.10E-01 |
GOTERM_BP_DIRECT | GO:0045860~positive regulation of protein kinase activity | 10 | 5.4 | 3.90E-05 | 5.40E-03 |
GOTERM_BP_DIRECT | GO:0051437~positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | 10 | 5.4 | 1.50E-03 | 7.30E-02 |
GOTERM_BP_DIRECT | GO:0032869~cellular response to insulin stimulus | 10 | 5.4 | 3.00E-02 | 4.70E-01 |
GOTERM_BP_DIRECT | GO:0031145~anaphase-promoting complex-dependent catabolic process | 10 | 5.4 | 5.70E-02 | 6.00E-01 |
GOTERM_BP_DIRECT | GO:0016925~protein sumoylation | 9 | 4.9 | 1.60E-03 | 7.60E-02 |
GOTERM_BP_DIRECT | GO:0007052~mitotic spindle organization | 9 | 4.9 | 2.80E-03 | 1.10E-01 |
GOTERM_BP_DIRECT | GO:1990090~cellular response to nerve growth factor stimulus | 8 | 4.3 | 1.20E-04 | 1.10E-02 |
GOTERM_BP_DIRECT | GO:0071407~cellular response to organic cyclic compound | 8 | 4.3 | 2.70E-04 | 1.90E-02 |
GOTERM_BP_DIRECT | GO:0006406~mRNA export from nucleus | 8 | 4.3 | 2.30E-02 | 4.20E-01 |
GOTERM_BP_DIRECT | GO:0000082~G1/S transition of mitotic cell cycle | 8 | 4.3 | 9.90E-02 | 7.50E-01 |
GOTERM_BP_DIRECT | GO:1900034~regulation of cellular response to heat | 7 | 3.8 | 1.10E-04 | 1.10E-02 |
GOTERM_BP_DIRECT | GO:0007067~mitotic nuclear division | 7 | 3.8 | 1.60E-04 | 1.40E-02 |
GOTERM_BP_DIRECT | GO:0043161~proteasome-mediated ubiquitin-dependent protein catabolic process | 7 | 3.8 | 1.80E-04 | 1.40E-02 |
GOTERM_BP_DIRECT | GO:0006297~nucleotide-excision repair, DNA gap filling | 7 | 3.8 | 2.00E-04 | 1.50E-02 |
GOTERM_BP_DIRECT | GO:1901796~regulation of signal transduction by p53 class mediator | 7 | 3.8 | 7.20E-04 | 4.20E-02 |
GOTERM_BP_DIRECT | GO:0006368~transcription elongation from RNA polymerase II promoter | 7 | 3.8 | 8.00E-04 | 4.40E-02 |
GOTERM_BP_DIRECT | GO:0000070~mitotic sister chromatid segregation | 7 | 3.8 | 2.20E-03 | 9.80E-02 |
GOTERM_BP_DIRECT | GO:0000398~mRNA splicing, via spliceosome | 7 | 3.8 | 3.60E-03 | 1.30E-01 |
GOTERM_BP_DIRECT | GO:0043547~positive regulation of GTPase activity | 7 | 3.8 | 5.20E-03 | 1.70E-01 |
GOTERM_BP_DIRECT | GO:0061418~regulation of transcription from RNA polymerase II promoter in response to hypoxia | 7 | 3.8 | 6.50E-03 | 1.90E-01 |
GOTERM_BP_DIRECT | GO:0006661~phosphatidylinositol biosynthetic process | 7 | 3.8 | 8.30E-03 | 2.30E-01 |