Table 8 The results of KEGG pathway enrichment analysis of lncRNAs target genes
Term ID | Description | Genes | Count | % | P-value | False Discovery Rate |
|---|---|---|---|---|---|---|
hsa05200 | Pathways in cancer | AKT1, BRAF, BCR, CREBBP, CRKL, KIT, TRAF3, ADCY4,ARNT, AXIN1, CTNNA1, COL4A3, CYCS, FZD6, GSK3B, LAMA4, LAMC1, PIK3R2, PTGER2, RBX1, STAT3, STAT5A, TCEB1 | 23 | 12.4 | 1.10E-05 | 2.50E-03 |
hsa05169 | Epstein-Barr virus infection | AKT1,CREBBP, POLR2H, POLR3C, POLR3K, TRAF3, XPO1, GSK3B, PIK3R2, PSMC6, PSMD11, PSMD14, STAT3, YWHAG | 14 | 7.6 | 1.10E-04 | 8.30E-03 |
hsa04110 | Cell cycle | BUB1, BUB3, CREBBP, ANAPC11, ANAPC2, CCNB1, GSK3B, ORC2, ORC3, RBX1, SMC3, YWHAG | 12 | 6.5 | 3.80E-05 | 4.10E-03 |
hsa05166 | HTLV-I infection | AKT1, BUB3, CREBBP, POLE, ADCY4, ANAPC11, ANAPC2, XPO1, FZD6, GSK3B, PIK3R2, STAT5A | 12 | 6.5 | 1.50E-02 | 1.50E-01 |
hsa03010 | Ribosome | RPL12, RPL30, RPL35, RPL37A, RPL38, RPL4, RPL8, RPS5, RPS7, RPS8, RPLP1 | 11 | 5.9 | 4.10E-04 | 1.80E-02 |
hsa05164 | Influenza A | AKT1, CREBBP, CYCS, XPO1, GSK3B, HNRNPUL1, PIK3R2, PABPN1, RAE1, SOCS3, TLR4 | 11 | 5.9 | 2.70E-03 | 7.10E-02 |
hsa03013 | RNA transport | RANBP2, RBM8A, UPF3A, EIF3J, EIF5B, XPO1, GEMIN4, GEMIN6, NUP205, RAE1 | 10 | 5.4 | 8.00E-03 | 1.10E-01 |
hsa05205 | Proteoglycans in cancer | AKT1, BRAF, IQGAP1, TIAM1, FZD6, PIK3R2, PPP1CC, PTPN6, STAT3, TLR4 | 10 | 5.4 | 2.00E-02 | 1.70E-01 |
hsa04932 | Non-alcoholic fatty liver disease | AKT1, NDUFB9, COX5A, COX7C, CYCS, GSK3B, PIK3R2, PRKAG1, SOCS3 | 9 | 4.9 | 1.10E-02 | 1.30E-01 |
hsa04062 | Chemokine signaling pathway | AKT1, BRAF, CRKL, TIAM1, ADCY4, GSK3B, PIK3R2, PRKCD, STAT3 | 9 | 4.9 | 3.50E-02 | 2.30E-01 |
hsa04510 | Focal adhesion | AKT1, BRAF, CRKL, COL4A3, GSK3B, LAMA4, LAMC1, PIK3R2, PPP1CC | 9 | 4.9 | 5.70E-02 | 3.10E-01 |
hsa04066 | HIF-1 signaling pathway | AKT1, CREBBP, ARNT, PIK3R2, RBX1, STAT3, TLR4, TCEB1 | 8 | 4.3 | 3.60E-03 | 8.30E-02 |
hsa04919 | Thyroid hormone signaling pathway | AKT1, CREBBP, GSK3B, MED13, NOTCH2, NOTCH4, NCOR1, PIK3R2 | 8 | 4.3 | 8.20E-03 | 1.00E-01 |
hsa05222 | Small cell lung cancer | AKT1, TRAF3, COL4A3, CYCS, LAMA4, LAMC1, PIK3R2 | 7 | 3.8 | 7.30E-03 | 1.10E-01 |
hsa04660 | T cell receptor signaling pathway | AKT1, CD4, GSK3B, LCP2, PIK3R2, PTPN6, PTPRC | 7 | 3.8 | 1.80E-02 | 1.60E-01 |
hsa04068 | FoxO signaling pathway | AKT1, BRAF, CREBBP, CCNB1, PIK3R2, PRKAG1, STAT3 | 7 | 3.8 | 5.40E-02 | 3.10E-01 |
hsa04630 | Jak-STAT signaling pathway | AKT1, CREBBP, PIK3R2, PTPN6, STAT3, STAT5A, SOCS3 | 7 | 3.8 | 7.40E-02 | 3.40E-01 |
hsa03015 | mRNA surveillance pathway | RBM8A, SMG1, SMG5, UPF3A, PABPN1, PPP1CC | 6 | 3.2 | 3.70E-02 | 2.40E-01 |
hsa04750 | Inflammatory mediator regulation of TRP channels | ADCY4, PIK3R2, PLA2G4F, PTGER2, PRKCD, PPP1CC | 6 | 3.2 | 4.80E-02 | 2.90E-01 |
hsa04330 | Notch signaling pathway | CREBBP, MAML2, NOTCH2, NOTCH4 | 4 | 2.2 | 7.30E-02 | 3.50E-01 |