Table 2 the validity of the algorithms
Algorithm | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|
(%, 95 CI) | (%, 95 CI) | (%, 95 CI) | (%, 95 CI) | (%, 95 CI) | |
High sensitivity | 94.2 | 93.7 | 79.2 | 98.5 | 93.8 |
(90.1–98.4) | (91.5–95.9) | (72.5–85.8) | (97.3–99.6) | (91.9–95.7) | |
High PPV | 75.2 | 98.3 | 91.9 | 94 | 93.6 |
(67.5–82.9) | (97.2–99.5) | (86.6–97.3) | (91.9–96.1) | (91.7–95.6) | |
High accuracy | 85.1 | 97.3 | 88.8 | 96.3 | 94.8 |
(78.8–91.5) | (95.8–98.7) | (83.1–94,5) | (94.6–98) | (93–96.6) | |
Balanced sensitivity and PPV | 89.3 | 96.2 | 85.7 | 97.2 | 94.8 |
(83.7–94.8) | (94.5–97.9) | (79.6–91.8) | (95.8–98.7) | (93.0–96.6) | |
Balanced specificity and NPV | 91.7 | 94.5 | 81.0 | 97.8 | 94.0 |
(86.8–96.6) | (92.5–96.6) | (74.5–87.6) | (96.5–99.2) | (92.1–95.9) | |
Combining high sensitivity and high PPV algorithms plus chart review | 94.2 | 98.3 | 93.4 | 98.5 | 97.5 |
(90.1–98.4) | (97.2–99.5) | (89.1–97.8) | (97.4–99.6) | (96.2–98.7) |