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Table 4 Univariate and multivariate Cox regression analyses Beclin-1 and ARID1A for the risk of death and recurrence in ICC patients

From: High Beclin-1 and ARID1A expression corelates with poor survival and high recurrence in intrahepatic cholangiocarcinoma: a histopathological retrospective study

  

Death

Recurrence

 

Crude HR

adjusted HR a

Crude HR

adjusted HR b

Beclin-1

Negative

1.0

1.0

1.0

1.0

 

Positive

2.39 (1.09–5.24)

2.51 (1.05–5.99)

2.27 (1.09–4.75)

1.85 (0.85–4.06)

ARID1A

Negative

1.0

1.0

1.0

1.0

 

Positive

1.59 (0.95–2.66)

1.95 (1.09–3.47)

1.71 (1.06–2.78)

2.08 (1.23–3.51)

  1. Bold indicates statistical significance, p < 0.05
  2. amodel controlled for age, GGT before surgery, ALP before surgery, CEA before surgery, number of lesions, tumor size, lymphatic metastasis, nerve invasion, involving extrahepatic tissue, mucus, tumor generalization, TNM stage.
  3. b model controlled for GGT before surgery, ALP before surgery, CEA before surgery, number of lesions, tumor size, lymphatic metastasis, involving extrahepatic tissue, necrosis, mucus, TNM stage.
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BMC Cancer

ISSN: 1471-2407

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