Fig. 2From: PPARγ activation serves as therapeutic strategy against bladder cancer via inhibiting PI3K-Akt signaling pathwayPPARγ agonists inhibited proliferation of bladder cancer cells. (a) Cell growth curve for Umuc-3 cells. (b) Cell growth curve for 5637 cells. Umuc-3 and 5637 cells were treated with pioglitazone, rosiglitazone, T0070907, and GW9662 (10, 20 μM) for 96 h. Cell proliferation was determined with CCK-8 every 24 h. Data are shown as mean ± standard deviation from triplicate experiments. * signifies p < 0.05; **, p < 0.01; compared with the control group treated with DMSO (0.1%)Back to article page