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Table 3 Comparison of the heart’s exposure to radiation between patients with and without cardiac events

From: The heart’s exposure to radiation increases the risk of cardiac toxicity after chemoradiotherapy for superficial esophageal cancer: a retrospective cohort study

 

CE

(n = 13)

Non-CE

(n = 67)

P value

Heart volume (mL)

679 (583–770)

660 (566–726)

0.5356

Heart Dmax (cGy)

6164 (6124–6261)

6092 (6030–6200)

0.0363

Heart Dmin (cGy)

46 (15–132)

35 (10–80)

0.5393

Heart Dmean (cGy)

3364 (2673–3882)

2920 (1763–3398)

0.0446

Percentage of the heart volume receiving more than indicated irradiation dose

V1500 cGy (%)

71.9 (55.8–82.6)

65.7 (40.6–75.0)

0.0976

V3000 cGy (%)

61.1 (47.0–70.0)

52.9 (28.9–64.1)

0.0669

V4000 cGy (%)

53.1 (41.3–62.3)

41.9 (20.9–53.4)

0.0266

V5000 cGy (%)

30.1 (20.8–37.2)

19.4 (10.3–28.2)

0.0167

Absolute heart volume receiving more than indicated irradiation dose

V1500 cGy (mL)

556 (327–627)

411 (272–498)

0.0699

V3000 cGy (mL)

432 (269–536)

341 (203–428)

0.0357

V4000 cGy (mL)

360 (222–468)

255 (142–364)

0.0202

V5000 cGy (mL)

193 (115–294)

134 (66–187)

0.0084

  1. Data are expressed as median (interquartile range). CE, cardiac event; Dmax, maximum dose; Dmin, minimum dose; Dmean, mean dose