Table 1 Clinical, laboratory, and pathological characteristics of UTUC and RCC groups
Variable | UTUC | RCC | p |
|---|---|---|---|
Female | 75 (56.8%) | 15 (24.6%) | < 0.001 |
Age (years) | 67.9 ± 9.5 | 57.07 ± 11.58 | < 0.001 |
Lifestyle | |||
 Chinese herb | 28 (25.0%) | 4 (6.6%) | 0.003 |
 Smoking | 27 (23.5%) | 16 (26.2%) | 0.686 |
Comorbidity | |||
 Hypertension | 50 (40.0%) | 31 (51.7%) | 0.134 |
 Diabetes mellitus | 29 (23.2%) | 16 (26.7%) | 0.607 |
 Hyperlipidemia | 8 (6.4%) | 3 (5.0%) | 0.706 |
 Hydronephrosis | 53 (47.3%) | 2 (3.3%) | < 0.001 |
 Pre-existing CKD | 101 (76.5%) | 15 (24.6%) | < 0.001 |
 Renal stone | 14 (12.7%) | 4 (6.6%) | 0.208 |
Laboratory data (Before nephrectomy) | |||
 BUN (mg/dl) | 21.77 ± 15.47 | 16.10 ± 10.94 | 0.015 |
 Crea (mg/dl) | 1.57 ± 1.30 | 1.14 ± 0.77 | 0.018 |
 eGFR (ml/min/m2, CKD-EPI) | 53.8 ± 24.7 | 80.0 ± 23.4 | < 0.001 |
 GPT (IU/L) | 25.08 ± 24.84 | 30.79 ± 26.39 | 0.161 |
 Albumin (mg/dl) | 3.75 ± 0.55 | 4.04 ± 0.51 | 0.017 |
 Na (mEq/L) | 137.31 ± 4.29 | 139.10 ± 2.53 | 0.021 |
 K (mEq/L) | 3.96 ± 0.44 | 3.94 ± 0.39 | 0.698 |
 WBC (× 1000/ul) | 7.70 ± 3.21 | 7.02 ± 1.91 | 0.126 |
 Hb (g/dL) | 11.60 ± 2.07 | 13.40 ± 2.08 | < 0.001 |
 PLT (×1000/ul) | 218.07 ± 76.62 | 229.30 ± 89.14 | 0.398 |
Renal histopathology | |||
Distribution of TI score | < 0.001* | ||
 0 | 13 (9.85%) | 23 (37.70%) | |
 1~4 | 47 (35.61%) | 28 (45.90%) | |
 5~8 | 64 (48.48%) | 8 (13.12%) | |
 ≧9 | 8 (6.06%) | 2 (3.28%) | |
Distribution of GGS rate | < 0.001* | ||
 0 | 24 (18.18%) | 2 (3.28%) | |
  > 0~10 | 33 (25.00%) | 36 (59.02%) | |
  > 10~25 | 29 (21.97%) | 18 (29.51%) | |
  > 25~50 | 26 (19.70%) | 3 (4.92%) | |
  > 50 (DGGS) | 20 (15.15%) | 2 (3.28%) | |
Adverse renal outcome | 22 | 4 | 0.056 |
 Creatinine doubling | 6 | 2 | |
 Dialysis | 16 | 2 | |
 Overall mortality | 45 | 15 | 0.019 |