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Fig. 1 | BMC Cancer

Fig. 1

From: Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy

Fig. 1

MTT assay of human glioblastoma U87MG and colorectal adenocarcinoma Caco-2 cell lines following treatment. a U87 MG and b Caco-2 cells were treated with different concentrations (indicated in the figure) of 5-FIC and 5-FU. DMSO was used as a vehicle control for both reagents. The Relative Absorbance values of 5-FIC and 5-FU treatment groups are shown as values obtained by measuring the intensity of the formazan at 550 nm, corrected for the background measured at 620 nm and normalized against the sample group treated with DMSO, the absorbance of which was considered as 1.0. Statistical significance indicated by p-values, where the hashtag symbol (#) designates p < 0.05, whereas the asterisk symbol (*) designates p < 0.0001 with respect to control (DMSO)

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