Table 4 Cox Proportional Hazard ratios, 95% Confidence intervals (95%CI) and p-values for survival analysis of relapse free survival dichotomised based on NUP98 expression above (high) and below the median (low) in (A)(i) all breast cancer samples, (A)(ii) all breast cancer samples excluding patients without systemic chemotherapy treatment, (B)(i) all TNBC samples, (A)(ii) all TNBC samples excluding patients without systemic chemotherapy treatment
KMplotter Relapse Free Survival | N(n) | HR | %95 CI | p-value | |
|---|---|---|---|---|---|
All Breast Cancer All Samples | |||||
Nup98 | low | 1984(671) | 1 | ||
high | 1984(602) | 0.95 | 00.85–1.06 | 0.37 | |
All Breast Cancer Untreated cases excluded | |||||
Nup98 | low | 940 (291) | 1 | ||
high | 940 (333) | 1.35 | 1.15–1.58 | 0.00016*** | |
TNBC All Cases | |||||
Nup98 | low | 128 (37) | 1 | ||
high | 128 (47) | 1.37 | 0.89–2.09 | 0.15 | |
TNBC Untreated cases excluded | |||||
Nup98 | low | 58 (13) | 1 | ||
high | 58 (25) | 2.07 | 1.05–3.97 | 0.025* | |