Fig. 3From: The neoepitope landscape of breast cancer: implications for immunotherapyCorrelations between predicted neoepitopes, mutational burden, and expressed neoepitopes. (a) The number of predicted binding neoepitopes (IEDB score ≤ 500 nM) is highly correlated (R2 = 0.86, p < 0.0001) with the number of nonsynonymous mutations across all breast cancers. (b) The number of predicted binding neoepitopes (IEDB score ≤ 500 nM) is highly correlated (R2 = 0.94, p < 0.0001) with the number of expressed neoepitopes (FPKM≥5) in all breast cancers. A fitted line from a linear regression is shown in red, with 95% CI levels shown in the grey shaded areasBack to article page