Fig. 5

miR-148b induces apoptosis in NSCLC cells. a Annexin V-FITC/PI double staining and flow cytometric analysis was applied to detect the apoptotic rate of PC14/B and A549 cells after being transfected with different mimics. b Early apoptotic rates obtained by quantification of results generated from graph A. the apoptotic rate of the miR-148b-overexpression cells was higher than the blank group, while the apoptotic rate of the miR-148b-lowexpression cells was below the blank group. The results are expressed as the mean ± standard deviation. PI, propidium iodide; Blank, cells transfected with unpackaged lentiviral vectors; NC, negative control; miR, microRNA