Fig. 5From: Increased NHE1 expression is targeted by specific inhibitor cariporide to sensitize resistant breast cancer cells to doxorubicin in vitro and in vivoCariporide enhances the sensitivity of cancerous tumors to doxorubicin in vivo. (a) Tumor tissues from each group were stained with H&E, while NHE1, cleaved PARP and caspase-3 expression in the tumor sections was characterized by immunohistochemistry. (b) Tissue lysates were subsequently prepared and subjected to western blotting analysis using the indicated antibodies. (c-e) Relative expression of MDR1, Bcl-2, and cleaved caspase-3 is shown in the histogramBack to article page