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Fig. 1 | BMC Cancer

Fig. 1

From: Increased NHE1 expression is targeted by specific inhibitor cariporide to sensitize resistant breast cancer cells to doxorubicin in vitro and in vivo

Fig. 1

Expression of NHE1 is altered in human breast cancer. (a) NHE1 expression in normal versus breast cancer tissues using publicly available datasets from The Cancer Genome Atlas (TCGA). (b) Zhao breast statistics. (c) Immunohistochemistry and western blot analysis of NHE1 protein expression in 20 paired primary breast cancer tissues and their corresponding adjacent tissues. (d) Western blot analysis of NHE-1 in different pathological stages. (e, f) Expression of NHE1 in sensitive MCF-7 and A2780 cell lines and drug-resistant MCF-7/ADR and A2780/PTX cells was assessed by RT-PCR and western blot. All graphs show the means±SD of three independent experiments

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