From: Squamous cell carcinoma transformation in mature cystic teratoma of the ovary: a systematic review
Variable | Univariate HR (95% CI) | P value |
---|---|---|
Age (n = 370) | ||
 <45 (n = 105) | Reference |  |
 ≥45 (n = 265) | 1.91 (1.26–2.89) | <0.01* |
Diameter (cm) (n = 265) (n = 265) | ||
 ≤10 (n = 67) | Reference |  |
 >10 (n = 198) | 1.08 (0.70–1.68) | 0.73 |
Stage (n = 348) | ||
 I (n = 172) | Reference |  |
 II (n = 70) | 6.92 (3.98–12.06) | <0.01* |
 III (n = 92) | 9.32 (5.58–15.59) | <0.01* |
 IV (n = 14) | 16.45(7.95–34.02) | <0.01* |
Grade (n = 169) | ||
 1 (n = 43) | Reference |  |
 2 (n = 69) | 1.60 (0.81–3.15) | 0.17 |
 3 (n = 57) | 1.76 (0.89–3.49) | 0.10 |