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Table 5 Clinical features and overall survival of SCC transformation in MCTO

From: Squamous cell carcinoma transformation in mature cystic teratoma of the ovary: a systematic review

Variable Univariate HR (95% CI) P value
Age (n = 370)
 <45 (n = 105) Reference  
 ≥45 (n = 265) 1.91 (1.26–2.89) <0.01*
Diameter (cm) (n = 265) (n = 265)
 ≤10 (n = 67) Reference  
 >10 (n = 198) 1.08 (0.70–1.68) 0.73
Stage (n = 348)
 I (n = 172) Reference  
 II (n = 70) 6.92 (3.98–12.06) <0.01*
 III (n = 92) 9.32 (5.58–15.59) <0.01*
 IV (n = 14) 16.45(7.95–34.02) <0.01*
Grade (n = 169)
 1 (n = 43) Reference  
 2 (n = 69) 1.60 (0.81–3.15) 0.17
 3 (n = 57) 1.76 (0.89–3.49) 0.10
  1. Cox proportional hazard regression model analysis