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Table 5 Clinical features and overall survival of SCC transformation in MCTO

From: Squamous cell carcinoma transformation in mature cystic teratoma of the ovary: a systematic review

Variable

Univariate HR (95% CI)

P value

Age (n = 370)

 <45 (n = 105)

Reference

 

 ≥45 (n = 265)

1.91 (1.26–2.89)

<0.01*

Diameter (cm) (n = 265) (n = 265)

 ≤10 (n = 67)

Reference

 

 >10 (n = 198)

1.08 (0.70–1.68)

0.73

Stage (n = 348)

 I (n = 172)

Reference

 

 II (n = 70)

6.92 (3.98–12.06)

<0.01*

 III (n = 92)

9.32 (5.58–15.59)

<0.01*

 IV (n = 14)

16.45(7.95–34.02)

<0.01*

Grade (n = 169)

 1 (n = 43)

Reference

 

 2 (n = 69)

1.60 (0.81–3.15)

0.17

 3 (n = 57)

1.76 (0.89–3.49)

0.10

  1. Cox proportional hazard regression model analysis