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Table 6 Hazard ratios and 95% confidence intervals for disease-free survival and overall survival, according to subtype admixture of Luminal A breast cancers in the TCGA validation cohort, Distance Ratio criteria only

From: Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes

 

Unadjusted

Adjusteda

HR

95% CI

HR

95% CI

Disease-free survival

 Tertile 1

1.00

–

1.00

–

 Tertile 2

1.19

0.51–2.81

1.14

0.48–2.74

 Tertile 3

2.73

1.35–5.48

2.85

1.39–5.85

 

Ptrend = 0.003

Ptrend = 0.002

Overall survival

 Tertile 1

1.00

–

1.00

–

 Tertile 2

1.45

0.75–2.79

1.34

0.69–2.62

 Tertile 3

1.73

0.95–3.14

1.90

1.02–3.54

 

Ptrend = 0.074

Ptrend = 0.040

  1. aAdjusted for age, stage and tumor size