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Table 1 Association between microtubule-associated protein Tau (MAPT) staining and prostate cancer phenotype

From: Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer

  

MAPT (%)

 

Parameter

N

Negative

Low

High

P

All cancers

12,313

91.8

7.1

1.1

 

Tumor stage

 pT2

7764

94.2

5.2

0.6

< 0.0001

 pT3a

2809

88.9

9.6

1.5

 pT3b-pT4

1688

85.7

11.7

2.6

Gleason grade

  ≤ 3 + 3

2072

96.4

3.3

0.3

< 0.0001

 3 + 4

6702

92.6

6.7

0.8

 3 + 4 Tertiary 5

614

91.0

8.1

0.8

 4 + 3

1257

88.5

9.7

1.8

 4 + 3 Tertiary 5

925

86.3

10.9

2.8

  ≥ 4 + 4

704

85.5

11.6

2.8

Lymph node metastasis

 N0

7604

91.3

7.5

1.2

< 0.0001

 N+

943

85.9

11.7

2.4

Preoperative PSA level (ng/ml)

  < 4

1418

89.6

8.9

1.6

0.0506

 4–10

7278

92.3

6.7

1.0

 10–20

2629

91.8

7.2

1.0

  > 20

918

91.8

7.3

0.9

Surgical margin

 Negative

9733

92.3

6.7

1.0

0.0011

 Positive

2536

90.0

8.6

1.3