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Fig. 1 | BMC Cancer

Fig. 1

From: Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

Fig. 1

CTC detection and recovery using modified RareCyte method. a. Workflow using modified AccuCyte sample processing developed for mouse blood. This involved RBC lysis to isolate nucleated cells, which were then processed onto slides using the AccuCyte method [13]. b. CTC recovery rate. The tumor cell recovery rate was 83% in the blood samples from non-tumor bearing mice spiked with ~ 500 BT474 cells (N = 3). No CTCs were found in control blood samples not spiked with BT474 cells

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