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Fig. 5 | BMC Cancer

Fig. 5

From: Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells

Fig. 5

Inhibiting effects of C.M. from ZA-pretreated MDA-MB-231 cells on Tregs migration. Tregs (5 × 10 4) were placed in the upper chambers for measurement of migration of Tregs into the lower chambers containing DMEM with 2% FBS with and without ZA and C.M. of MDA-MB-231 cells with and without ZA pretreatment. The relative percentages of migrated cells are shown compared with that of C.M. of MDA-MB-231 cells without ZA. Values indicate means ± SEM of results from three independent experiments performed in duplicate. Significant differences in percentage were determined using one-way ANOZA; ** P < 0.01; *** P < 0.001

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