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Table 2 Clinical and pathologic characteristics of the cases with EGFR single/compound mutation

From: Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma

Parameter Subtype Single (n = 57) Compound (n = 7) P-value
aMean age (mean ± SD); yrs 66.4 ± 9.6 66.7 ± 9.3 0.94
bSex, n (%) Male 23 1 0.24
Female 34 6
bSmoking habit, n (%) No 31 6 0.22
Yes 26 1
bEGFR mutation, n (%) L858R 38 4 0.0052*
Exon19del 17 0
G719A/S 2 3
aTumor size (mean ± SD); mm   22.5 ± 8.9 33.7 ± 23.3 0.014*
bpStage, n (%) IA 37 2 0.012*
IB 13 1
IIA-IIIB 7 4
  1. aP-value was obtained from t-test
  2. bP-value was obtained from Fisher’s test
  3. A value of p < 0.05 was marked "*"