Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma

Table 2 Clinical and pathologic characteristics of the cases with EGFR single/compound mutation

Parameter	Subtype	Single (n = 57)	Compound (n = 7)	P-value
^aMean age (mean ± SD); yrs		66.4 ± 9.6	66.7 ± 9.3	0.94
^bSex, n (%)	Male	23	1	0.24
^bSex, n (%)	Female	34	6	0.24
^bSmoking habit, n (%)	No	31	6	0.22
^bSmoking habit, n (%)	Yes	26	1	0.22
^bEGFR mutation, n (%)	L858R	38	4	0.0052*
	Exon19del	17	0
	G719A/S	2	3
^aTumor size (mean ± SD); mm		22.5 ± 8.9	33.7 ± 23.3	0.014*
^bpStage, n (%)	IA	37	2	0.012*
	IB	13	1
	IIA-IIIB	7	4

ISSN: 1471-2407